CTLA4 is differently associated with autoimmune diseases in the Dutch population
نویسندگان
چکیده
منابع مشابه
Variants of the CTLA4 gene that segregate with autoimmune diseases are not associated with endometriosis.
An autoimmune etiology has been suggested for endometriosis mostly on the basis of an increased prevalence of autoimmune diseases in affected women. Cytotoxic T lymphocyte antigen (CTLA) 4 gene is recognized as a primary determinant for autoimmunity since specific polymorphisms have been associated with predisposition to most autoimmune disorders. This study was aimed to evaluate whether two va...
متن کاملthe ctla4 -819 c/t dimorphism is associated with type 1 diabetes in egyptian children
background : we investigated whether the c-819t snp of the ctla4 gene is associated with type 1 diabetes (t1d) for the egyptian population, a multi-ethnic group. we determined if expression of the c-819t snp correlated with onset of t1d for egyptian children and the prevalence of this polymorphism with respect to gender. methods: the association of the c-819t snp in intron 1 of the ctla-4 gene...
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Background: CCL22/MDC is a CC chemokine with a critical role in regulation of the immune balance in physiological condition. CCL22/CCR-4 ligation has been documented to participate in the migration of regulatory T (Treg) cells and Th2 lymphocytes to the site of breast tumors; circumstances that are known to be associated with poor prognosis. Objective: To investigate the association of a single...
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ژورنال
عنوان ژورنال: Human Genetics
سال: 2005
ISSN: 0340-6717,1432-1203
DOI: 10.1007/s00439-005-0087-8